- Dead Rising 2
- Dead Space 3
- Dead Space 3: Awakened
- Dead Synchronicity: Tomorrow Comes Today
- Dead Trigger
- Deadlight
- Death Cargo
- Death Crown
- Death to Spies: Moment of Truth
- DeathSpank: Thongs of Virtue
- Decromancer
- Deep Down
- Deep Space Settlement
- Defect
- Defenders of Time
- Defense Grid 2
- Deformers
- Dementium 2
- Demon Skin
- Demon's Souls [I/2009]
- Descent [II/2023]
- Desert Law
- Deus Ex: Mankind Divided
- Devil May Cry 4
- Diablo 3
- Diluvian Ultra
- Dino Crisis 3
- Dino D-Day
- Disgaea 4: A Promise Revisited
- Dishonored
- Dishwasher: Vampire Smile, The
- Disney Infinity
- Divinity 2: Ego Draconis
- DmC: Devil May Cry
- Doctor Who: The Eternity Clock
- DodoGo!
- DogFighter
- Don't Knock Twice
- Don't Starve
- Doodle Hex
- Doom [I/1993]
- Doorways
- Doorways: The Underworld
- Dorfromantik
- Down the Mountain
- Dracula 4: The Shadow of the Dragon
- Dragon Age 2
- Dragon Age: Inquisition
- Dragon Fin Soup
- Dragon Quest 10: Rise of the Five Tribes Offline
- Dragon Wars
- Dragons and Titans
- Dragon's Dogma
- Dragon's Prophet
- Drakensang Online
- Draw Slasher
- Drawn to Death
- Dread Templar
- Dreadline
- Dreadnought [II/2017]
- Dream Trigger 3D
- Dreamfall Chapters
- Dreamfall: The Longest Journey
- Dreamkiller
- Duke Nukem Forever
- Dungeon Defenders
- Dungeon Defiler
- Dungeon Keeper 2
- Dungeons
- Dungeons of Dredmor
- DUST 514
- Dustwind
- E.T. Armies
- EA Sports FIFA Online 4
- Eador: Masters of the Broken World - Allied Forces
- Earthworm Jim [I/1994]
- East India Company
- Easter Egg Invaders
- Edna & Harvey: Harvey's New Eyes
- Edna and Harvey: The Breakout
- eFootball 2022
- Eisenhorn: Xenos
- Elder Scrolls 3: Morrowind, The
- Elder Scrolls 4: Oblivion, The
- Elder Scrolls 5: Skyrim, The
- Elite Dangerous
- Elite vs. Freedom
- Emperor: Battle for Dune
- Empire: Total War
- Endless Legend: Shadows
- Endless Space
- Enemy Territory: Quake Wars
- Enjoy Your Massage!
- Epigenesis
- escapeVektor
- Euro Truck Simulator 2
- Euro Truck Simulator 2: Vive la France!
- Europa Universalis 4
- EVE Online
- EVE: Valkyrie